Einträge von pfabian

Human Frontier Science Program Grant for modelling the electric field in enzyme catalysis

An international and interdisciplinary team of scientists, comprising Stefan Wuttke from BCMaterials (Spain) and Steven Boxer from Stanford University (USA), has received a prestigious three-year Human Frontier Science Program Research (HFSP) Grant. The project aims to study and understand the physical basis of enzyme catalysis. Enzymes are remarkable biological catalysts responsible for driving complex metabolic reactions […]

Toxicity of Metal-Organic Framework Nanoparticles: From Essential Analyses to Potential Applications

Owing to their immense design versatility, the number of novel metal-organic framework (MOF) structures and their proposed applications, especially for MOF nanoparticles, is exponentially increasing (Figure 1). But although the potential hazards of such nanosized particles have become evident, a systemic hazard assessment of MOF nanoparticles, including the evaluation of their toxicity as well as […]

MOF Synthesis Prediction via Automatic Data Mining and Machine Learning

The design and functionalization of materials is a cornerstone of synthetic chemistry. Since its discovery, a quarter of a century ago, reticular synthesis — linking molecular building units by strong bonds into 2D and 3D extended crystalline porous metal-organic frameworks (MOFs) — has been added to the repertoire of synthetic chemists. Reticular chemistry operates in […]

Nanoscience versus Viruses: The SARS-CoV-2 Case

The current health crisis caused by the spread of coronavirus (SARS-CoV-2) has grounded humanity in unprecedented ways. Our stores of knowledge and laboratories of creation were shuttered, and we experienced the reality of ‘lockdown’. As researchers sitting in their homes hiding from this invisible invader and watching helplessly its destruction of innocent lives, we are […]

21st Century Materials

Emerging Scholars at the Frontiers Symposium The „21st Century Materials: Emerging Scholars at the Frontiers“ Symposium aims to discuss the most recent advancements in Materials Science delivered by emerging scholars at the frontiers.  The symposium is jointly organized by the Berkeley Global Science Institute (Prof. Omar Yaghi, USA), Basque Center for Materials (Prof. Stefan Wuttke, Spain), and College of Science at […]

Augmented Reticular Chemistry

Our recent presents a synthetic approach to building structures at the macroscopic scale by introducing the idea of augmented reticular chemistry — crystals of metal-organic framework (MOF) are connected by strong bonds into superframeworks (Figure). This strategy escalates the size of the building blocks from molecules to crystals and brings about progression from MOFs to […]

25 Years of Reticular Chemistry

The design and synthesis of materials is a cornerstone of synthetic chemistry. Since its discovery a quarter of a century ago, reticular synthesis of 2D and 3D extended crystalline porous metal-organic frameworks (MOFs) and covalent organic frameworks (COFs) has been added to the repertoire of synthetic chemists. In 25 Years of Reticular Chemistry we highlight […]

Modular assembly of red blood cells with metal-organic frameworks

A closer look inside living matter has revealed that basic units of living beings, such as proteins, nucleic acids, and macromolecular assemblies, have sizes on the nanometer scale. Interestingly, these basic units present spectacular reactivity and chemical specificity that were naturally optimized through life evolution. However natural evolution has so far failed to incorporate into […]

Special Issue: Functionalization chemistry of porous materials

Chemists are naturally more interested in what is there rather than what is not. We are spontaneously drawn to the chemical core of compounds and materials: the atoms, the ways in which they are connected and their interactions with electromagnetic radiation, other atoms/molecules or even biological systems. However, when it comes to porous materials we […]

Talk: Plenty of Room at the Top

The maturation of synthetic methodologies over the past century has transformed chemistry from a largely empirical to a rational science. Following this golden era of chemical synthesis, any thermodynamically stable molecule can be synthesized given enough resources and time. At this point in time, an apparent lack of major challenges in the field has been […]